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Ceramide-induced BOK promotes mitochondrial fission in preeclampsia

20 Feb 2018

Abstract excerpt

Mitochondria are in a constant balance of fusing and dividing in response to cellular cues. Fusion creates healthy mitochondria, whereas fission results in removal of non-functional organelles. Changes in mitochondrial dynamics typify several human diseases. However, the contribution of mitochondrial dynamics to preeclampsia, a hypertensive disorder of pregnancy characterized by placental cell autophagy and...

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PMID: 29463805
DOI: 10.1038/s41419-018-0360-0

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