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Article

Strain-dependent effects of clinical echovirus 30 outbreak isolates at the blood-CSF barrier

20 Feb 2018

Abstract excerpt

BACKGROUND: Echovirus (E) 30 (E-30) meningitis is characterized by neuroinflammation involving immune cell pleocytosis at the protective barriers of the central nervous system (CNS). In this context, infection of the blood-cerebrospinal fluid barrier (BCSFB), which has been demonstrated to be involved in enteroviral CNS pathogenesis, may affect the tight junction (TJ) and adherens junction (AJ) function and...

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PMID: 29463289
DOI: 10.1186/s12974-018-1061-4

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