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Article

New ADCY3 Variants Dance in Obesity Etiology.

Trends in endocrinology and metabolism: TEM - 1 Jun 2018

Tian Yan, Peng Boqiang, Fu Xianghui

Abstract excerpt

The genetic etiology for obesity-related traits remains elusive. Recent studies link novel ADCY3 variants to obesity and diabetes, and identify an important role of ADCY3-mediated signaling at neuronal primary cilia in the predisposition of obesity. These findings provide new information on obesity etiology and suggest potential anti-obesity therapeutic strategies.

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Identifiers

PMID: 29454745
DOI: 10.1016/j.tem.2018.02.004

Genes

ADCY3

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