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Article

Repeated Administrations of Cardiac Progenitor Cells Are Superior to a Single Administration of an Equivalent Cumulative Dose.

Journal of the American Heart Association - 13 Feb 2018

Tang Xian-Liang, Nakamura Shunichi, Li Qianhong, Wysoczynski Marcin, Gumpert Anna M, Wu Wen-Jian, Hunt Greg, Stowers Heather, Ou Qinghui, Bolli Roberto

Abstract excerpt

BACKGROUND: We have recently found that 3 repeated doses (12×106 each) of c-kitPOS cardiac progenitor cells (CPCs) were markedly more effective than a single dose of 12×106 cells in alleviating postinfarction left ventricular dysfunction and remodeling. However, since the single-dose group received only one third of the total number of CPCs given to the multiple-dose group, it is unknown whether the superior...

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Identifiers

PMID: 29440036
DOI: 10.1161/JAHA.117.007400
PMCID: PMC5850187

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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