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Article

Endoglin and alk1 as therapeutic targets for hereditary hemorrhagic telangiectasia.

Expert opinion on therapeutic targets - 1 Oct 2017

Ruiz-Llorente Lidia, Gallardo-Vara Eunate, Rossi Elisa, Smadja David M, Botella Luisa M, Bernabeu Carmelo

Abstract excerpt

INTRODUCTION: Hereditary Haemorrhagic Telangiectasia (HHT) is as an autosomal dominant trait characterized by frequent nose bleeds, mucocutaneous telangiectases, arteriovenous malformations (AVMs) of the lung, liver and brain, and gastrointestinal bleedings due to telangiectases. HHT is originated by mutations in genes whose encoded proteins are involved in the transforming growth factor β (TGF-β) family...

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Identifiers

PMID: 28796572
DOI: 10.1080/14728222.2017.1365839

Genes

ENG
ACVRL1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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