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Retinal progenitor cells release extracellular vesicles containing developmental transcription factors, microRNA and membrane proteins

6 Feb 2018

Abstract excerpt

A range of cell types, including embryonic stem cells, neurons and astrocytes have been shown to release extracellular vesicles (EVs) containing molecular cargo. Across cell types, EVs facilitate transfer of mRNA, microRNA and proteins between cells. Here we describe the release kinetics and content of EVs from mouse retinal progenitor cells (mRPCs). Interestingly, mRPC derived EVs contain mRNA, miRNA and...

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PMID: 29434302
DOI: 10.1038/s41598-018-20421-1

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