Article
Polymorphisms in the SP110 and TNF-α Gene and Susceptibility to Pulmonary and Spinal Tuberculosis among Southern Chinese Population.
Disease markers - 1 Jan 2017
Zhou Ying, Tan Chun-Yan, Mo Zhi-Jiang, Gao Qi-le, He Dan, Li Jiong, Huang Rong-Fu, Li Yan-Bing, Guo Chao-Feng, Guo Qiang, Wang Long-Jie, Yang Guan-Teng, Zhang Hong-Qi
Abstract excerpt
OBJECTIVE: To investigate the association of single-nucleotide polymorphisms (SNPs) in SP110 gene and TNF-α gene among pulmonary TB (PTB) and spinal TB (STB) patients. METHODS: In a total of 190 PTB patients, 183 STB patients were enrolled as the case group and 362 healthy individuals at the same geographical region as the control group. The SP110 SNPs (rs722555 and rs1135791) and the promoter -308G>A (rs1800629)...
Read the complete abstract on PubMed