Article
Genome-Wide Association Study in African Americans with Acute Respiratory Distress Syndrome Identifies the Selectin P Ligand Gene as a Risk Factor.
American journal of respiratory and critical care medicine - 1 Jun 2018
Bime Christian, Pouladi Nima, Sammani Saad, Batai Ken, Casanova Nancy, Zhou Tong, Kempf Carrie L, Sun Xiaoguang, Camp Sara M, Wang Ting, Kittles Rick A, Lussier Yves A, Jones Tiffanie K, Reilly John P, Meyer Nuala J, Christie Jason D, Karnes Jason H, Gonzalez-Garay Manuel, Christiani David C, Yates Charles R, Wurfel Mark M, Meduri Gianfranco U, Garcia Joe G N
Abstract excerpt
RATIONALE: Genetic factors are involved in acute respiratory distress syndrome (ARDS) susceptibility. Identification of novel candidate genes associated with increased risk and severity will improve our understanding of ARDS pathophysiology and enhance efforts to develop novel preventive and therapeutic approaches. OBJECTIVES: To identify genetic susceptibility targets for ARDS. METHODS: A genome-wide association...
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