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Article

Chromosomal instability in women with primary ovarian insufficiency.

Human reproduction (Oxford, England) - 1 Mar 2018

Katari Sunita, Aarabi Mahmoud, Kintigh Angela, Mann Susan, Yatsenko Svetlana A, Sanfilippo Joseph S, Zeleznik Anthony J, Rajkovic Aleksandar

Abstract excerpt

STUDY QUESTION: What is the prevalence of somatic chromosomal instability among women with idiopathic primary ovarian insufficiency (POI)? SUMMARY ANSWER: A subset of women with idiopathic POI may have functional impairment in DNA repair leading to chromosomal instability in their soma. WHAT IS KNOWN ALREADY: The formation and repair of DNA double-strand breaks during meiotic recombination are fundamental...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29425284
DOI: 10.1093/humrep/dey012
PMCID: PMC6454535

Genes

CETN2
HAUS7
MLH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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