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Article

New Developments in Genetic rat models of Parkinson's Disease.

Movement disorders : official journal of the Movement Disorder Society - 1 May 2018

Creed Rose B, Goldberg Matthew S

Abstract excerpt

Preclinical research on Parkinson's disease has relied heavily on mouse and rat animal models. Initially, PD animal models were generated primarily by chemical neurotoxins that induce acute loss of dopaminergic neurons in the substantia nigra. On the discovery of genetic mutations causally linked to PD, mice were used more than rats to generate laboratory animals bearing PD-linked mutations because mutagenesis...

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Source

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Identifiers

PMID: 29418019
DOI: 10.1002/mds.27296
PMCID: PMC5992003

Genes

PINK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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