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Article

Parkinson’s disease: genetic versus toxin‐induced rodent models

14 Feb 2008

Abstract excerpt

Parkinson's disease (PD), a common progressive neurodegenerative disorder, is characterized by degeneration of dopamine neurons in the substantia nigra and neuronal proteinaceous aggregates called Lewy bodies (LBs). The etiology of PD is probably a combination of environmental and genetic factors. Recent progress in molecular genetics has identified several genes causing PD, including alpha-synuclein,...

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PMID: 18279376
DOI: 10.1111/j.1742-4658.2008.06302.x

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