Article
A Genome-Wide Association Study in Hispanics/Latinos Identifies Novel Signals for Lung Function. The Hispanic Community Health Study/Study of Latinos.
American journal of respiratory and critical care medicine - 15 Jul 2018
Burkart Kristin M, Sofer Tamar, London Stephanie J, Manichaikul Ani, Hartwig Fernando P, Yan Qi, Soler Artigas María, Avila Lydiana, Chen Wei, Davis Thomas Sonia, Diaz Alejandro A, Hall Ian P, Horta Bernardo L, Kaplan Robert C, Laurie Cathy C, Menezes Ana M, Morrison Jean V, Oelsner Elizabeth C, Rastogi Deepa, Rich Stephen S, Soto-Quiros Manuel, Stilp Adrienne M, Tobin Martin D, Wain Louise V, Celedón Juan C, Barr R Graham
Abstract excerpt
RATIONALE: Lung function and chronic obstructive pulmonary disease (COPD) are heritable traits. Genome-wide association studies (GWAS) have identified numerous pulmonary function and COPD loci, primarily in cohorts of European ancestry. OBJECTIVES: Perform a GWAS of COPD phenotypes in Hispanic/Latino populations to identify loci not previously detected in European populations. METHODS: GWAS of lung function and...
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