Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

PBX3 Is Part of an EMT Regulatory Network and Indicates Poor Outcome in Colorectal Cancer

1 Feb 2018

Abstract excerpt

Abstract Purpose: Colorectal cancers are composed of phenotypically different tumor cell subpopulations within the same core genetic background. Here, we identify high expression of the TALE transcription factor PBX3 in tumor cells undergoing epithelial–mesenchymal transition (EMT), analyze PBX3 regulation, and determine clinical associations in colorectal cancer. Experimental design: We used transcriptomic and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Digestive system and related health
Share to Genetic factors in colorectal cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29391352
DOI: 10.1158/1078-0432.ccr-17-2572

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

PBX3 Is Part of an EMT Regulatory Network and Indicates Poor Outcome in Colorectal CancerPMID 29391352Read ↗

PBX3 promotes migration and invasion of colorectal cancer cells via activation of MAPK/ERK signaling pathwaySemantic proximity Read ↗

Comprehensive Analysis of the Expression, Prognostic Value and Correlations with Immune Infiltration of PBX Family Members in Colorectal CancerSemantic proximity Read ↗

TBX3 acts as tissue-specific component of the Wnt/β-catenin enhanceosomeSemantic proximity Read ↗

PTBP3-Mediated Regulation of ZEB1 mRNA Stability Promotes Epithelial–Mesenchymal Transition in Breast CancerSemantic proximity Read ↗

GLI3 Promotes Invasion and Predicts Poor Prognosis in Colorectal CancerSemantic proximity Read ↗

PBX3/MEK/ERK1/2/LIN28/let-7b positive feedback loop enhances mesenchymal phenotype to promote glioblastoma migration and invasion.Semantic proximity Read ↗

Comprehensive Analysis of Prognostic Value and Immune Infiltration of Chromobox Family Members in Colorectal CancerSemantic proximity Read ↗

The Developmental Transcription Factor TBX3 Physically Engages with the Wnt/β-catenin Transcriptional Complex in Human Colorectal Cancer Cells to Regulate Metastasis GenesSemantic proximity Read ↗

Clinical Correlation of Transcription Factor SOX3 in Cancer: Unveiling Its Role in TumorigenesisSemantic proximity Read ↗

Loss of PEX26 promotes migration, invasion, and EMT via activating Wnt pathway in colorectal cancerSemantic proximity Read ↗

AKT3 Expression in Mesenchymal Colorectal Cancer Cells Drives Growth and Is Associated with Epithelial-Mesenchymal TransitionSemantic proximity Read ↗

BTF3-mediated regulation of BMI1 promotes colorectal cancer through influencing epithelial-mesenchymal transition and stem cell-like traits.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.