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Article

IL-13 regulates human nasal epithelial cell differentiation via H3K4me3 modification

1 Jan 2018

Abstract excerpt

INTRODUCTION: Epigenetic regulation has been shown to play an important role in the development of inflammatory diseases, including chronic rhinosinusitis and nasal polyps. The latter are characterized by epithelial mis-differentiation and infiltration of inflammatory cytokines. H3K4me3 has been shown to be involved in regulating lineage commitment. However, the underlying mechanisms, especially in human nasal...

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PMID: 29386911
DOI: 10.2147/jir.s149156

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