Article
Curcumin on the "flying carpets" to modulate different signal transduction cascades in cancers: Next-generation approach to bridge translational gaps.
Journal of cellular biochemistry - 1 Jun 2018
Celik Hulya, Aydin Tuba, Solak Kubra, Khalid Sumbul, Farooqi Ammad A
Abstract excerpt
Curcumin, a bioactive and pharmacologically efficient component isolated from Curcuma longa has attracted considerable attention because of its ability to modulate diverse cellular and physiological pathways. WNT, TGF/SMAD, NOTCH, and SHH are fundamentally different signaling cascades, but their choreographed activation is strongly associated with cancer development and progression. In this review we have...
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