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Article

Quantitative or qualitative transcriptional diagnostic signatures? A case study for colorectal cancer

29 Jan 2018

Abstract excerpt

BACKGROUND: Due to experimental batch effects, the application of a quantitative transcriptional signature for disease diagnoses commonly requires inter-sample data normalization, which would be hardly applicable under common clinical settings. Many cancers might have qualitative differences with the non-cancer states in the gene expression pattern. Therefore, it is reasonable to explore the power of qualitative...

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PMID: 29378509
DOI: 10.1186/s12864-018-4446-y

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