Article
Isolation of circulating plasma cells from blood of patients diagnosed with clonal plasma cell disorders using cell selection microfluidics.
Integrative biology : quantitative biosciences from nano to macro - 19 Feb 2018
Kamande Joyce W, Lindell Maria A M, Witek Małgorzata A, Voorhees Peter M, Soper Steven A
Abstract excerpt
Blood samples from patients with plasma cell disorders were analysed for the presence of circulating plasma cells (CPCs) using a microfluidic device modified with monoclonal anti-CD138 antibodies. CPCs were immuno-phenotyped using a CD38/CD56/CD45 panel and identified in 78% of patients with monoclonal gammopathy of undetermined significance (MGUS), all patients with smouldering and symptomatic multiple myeloma...
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