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Article

Increased expression of YAP1 in prostate cancer correlates with extraprostatic extension

1 Jan 2017

Abstract excerpt

Objective: Yes associated protein 1 (YAP1) is a member of the Hippo pathway, acting as a transcriptional coactivator. To elucidate the role of YAP1 and phosphorylated (p)YAP1 in prostate cancer (PCa) tumorigenesis, we investigated their expression in clinical samples of PCa and cell lines. Methods: Fifty-four tumor, adjacent nontumor, and prostate intraepithelial neoplasia (PIN) tissues from patients with PCa...

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Share to Hippo pathway signaling and YAP/TAZ
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PMID: 29372107
DOI: 10.20892/j.issn.2095-3941.2017.0083

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