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Article

Immune gene expression and response to chemotherapy in advanced breast cancer

25 Jan 2018

Abstract excerpt

BACKGROUND: Transcriptomic profiles have shown promise as predictors of response to neoadjuvant chemotherapy in breast cancer (BC). This study aimed to explore their predictive value in the advanced BC (ABC) setting. METHODS: In a Phase 3 trial of first-line chemotherapy in ABC, a fine needle aspiration biopsy (FNAB) was obtained at baseline. Intrinsic molecular subtypes and gene modules related to immune...

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PMID: 29370583
DOI: 10.1038/bjc.2017.446

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