Prognostic Impact of a 12-gene Progression Score in Non-muscle-invasive Bladder Cancer: A Prospective Multicentre Validation Study.

doi:10.1016/j.eururo.2017.05.040

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Article

Prognostic Impact of a 12-gene Progression Score in Non-muscle-invasive Bladder Cancer: A Prospective Multicentre Validation Study.

European urology - 1 Sept 2017

Dyrskjøt Lars, Reinert Thomas, Algaba Ferran, Christensen Emil, Nieboer Daan, Hermann Gregers G, Mogensen Karin, Beukers Willemien, Marquez Mirari, Segersten Ulrika, Høyer Søren, Ulhøi Benedicte P, Hartmann Arndt, Stöhr Robert, Wach Sven, Nawroth Roman, Schwamborn Kristina, Tulic Cane, Simic Tatjana, Junker Kerstin, Harving Niels, Petersen Astrid C, Jensen Jørgen B, Keck Bastian, Grimm Marc-Oliver, Horstmann Marcus, Maurer Tobias, Steyerberg Ewout W, Zwarthoff Ellen C, Real Francisco X, Malats Núria, Malmström Per-Uno, Ørntoft Torben F

Abstract excerpt

BACKGROUND: Progression of non-muscle-invasive bladder cancer (NMIBC) to muscle-invasive bladder cancer (MIBC) is life-threatening and cannot be accurately predicted using clinical and pathological risk factors. Biomarkers for stratifying patients to treatment and surveillance are greatly needed. OBJECTIVE: To validate a previously developed 12-gene progression score to predict progression to MIBC in a large,...

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PMID: 28583312
DOI: 10.1016/j.eururo.2017.05.040

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