Article
Unconventional myosin VIIA promotes melanoma progression.
Journal of cell science - 22 Feb 2018
Liu Yuqing, Wei Xiaofan, Guan Lizhao, Xu Sidi, Yuan Yang, Lv Danyu, He Xiaokun, Zhan Jun, Kong Yan, Guo Jun, Zhang Hongquan
Abstract excerpt
Unconventional myosin VIIA (Myo7a) is an actin-based motor molecule that normally functions in the cochlear hair cells of the inner ear. Mutations of MYO7A/Myo7a have been implicated in inherited deafness in both humans and mice. However, there is limited information about the functions of Myo7a outside of the specialized cells of the ears. Herein, we report a previously unidentified function of Myo7a by...
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