Article
Risk of Different Cancers Among First-degree Relatives of Pancreatic Cancer Patients: Influence of Probands' Susceptibility Gene Mutation Status.
Journal of the National Cancer Institute - 1 Mar 2019
Antwi Samuel O, Fagan Sarah E, Chaffee Kari G, Bamlet William R, Hu Chunling, Polley Eric C, Hart Steven N, Shimelis Hermela, Lilyquist Jenna, Gnanaolivu Rohan D, McWilliams Robert R, Oberg Ann L, Couch Fergus J, Petersen Gloria M
Abstract excerpt
BACKGROUND: Increased risk of malignancies other than pancreatic cancer (PC) has been reported among first-degree relatives (FDRs) of PC patients; however, the roles of susceptibility gene mutations are unclear. We assessed risk for 15 cancers among FDRs of unselected PC probands. METHODS: Data on 17 162 FDRs, with more than 336 000 person-years at risk, identified through 2305 sequential PC probands enrolled at...
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