Article
FANCM and RECQL genetic variants and breast cancer susceptibility: relevance to South Poland and West Ukraine.
BMC medical genetics - 19 Jan 2018
Nguyen-Dumont Tú, Myszka Aleksander, Karpinski Pawel, Sasiadek Maria M, Akopyan Hayane, Hammet Fleur, Tsimiklis Helen, Park Daniel J, Pope Bernard J, Slezak Ryszard, Kitsera Nataliya, Siekierzynska Aleksandra, Southey Melissa C
Abstract excerpt
BACKGROUND: FANCM and RECQL have recently been reported as breast cancer susceptibility genes and it has been suggested that they should be included on gene panel tests for breast cancer predisposition. However, the clinical value of testing for mutations in RECQL and FANCM remains to be determined. In this study, we have characterised the spectrum of FANCM and RECQL mutations in women affected with breast or...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.