Article
Implementation of Standardized Clinical Processes for TPMT Testing in a Diverse Multidisciplinary Population: Challenges and Lessons Learned.
Clinical and translational science - 1 Mar 2018
Weitzel Kristin W, Smith D Max, Elsey Amanda R, Duong Benjamin Q, Burkley Benjamin, Clare-Salzler Michael, Gong Yan, Higgins Tara A, Kong Benjamin, Langaee Taimour, McDonough Caitrin W, Staley Benjamin J, Vo Teresa T, Wake Dyson T, Cavallari Larisa H, Johnson Julie A
Abstract excerpt
Although thiopurine S-methyltransferase (TPMT) genotyping to guide thiopurine dosing is common in the pediatric cancer population, limited data exist on TPMT testing implementation in diverse, multidisciplinary settings. We established TPMT testing (genotype and enzyme) with clinical decision support, provider/patient education, and pharmacist consultations in a tertiary medical center and collected data over 3...
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