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Article

Identification of Individual Bacterial Cells through the Intermolecular Interactions with Peptide-Functionalized Solid-State Pores.

Analytical chemistry - 6 Feb 2018

Tsutsui Makusu, Tanaka Masayoshi, Marui Takahiro, Yokota Kazumichi, Yoshida Takeshi, Arima Akihide, Tonomura Wataru, Taniguchi Masateru, Washio Takashi, Okochi Mina, Kawai Tomoji

Abstract excerpt

Bioinspired pore sensing for selective detection of flagellated bacteria was investigated. The Au micropore wall surface was modified with a synthetic peptide designed from toll-like receptor 5 (TLR5) to mimic the pathogen-recognition capability. We found that intermolecular interactions between the TLR5-derived recognition peptides and flagella induce ligand-specific perturbations in the translocation dynamics...

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PMID: 29350898
DOI: 10.1021/acs.analchem.7b04950

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TLR5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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