Article
[Resistance to integrase inhibitors].
Enfermedades infecciosas y microbiologia clinica - 1 Nov 2008
Garrido Carolina, de Mendoza Carmen, Soriano Vicente
Abstract excerpt
Integrase inhibitors are the most recently approved family of antiretroviral agents for the treatment of HIV infection. As with other antiretroviral agents, under pharmacological pressure, the virus selects resistance mutations if viral suppression is incomplete. Mutations are selected in the integrase gene, specifically in positions proximal to the catalytic center. Because clinical experience with these drugs...
Topics
Join the communities discussing this publication.