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Article

Validation of the digital PCR system in tyrosine kinase inhibitor-resistant EGFR mutant non-small-cell lung cancer.

Pathology international - 1 Mar 2018

Masago Katsuhiro, Fujita Shiro, Hata Akito, Okuda Chiyuki, Yoshizumi Yuko, Kaji Reiko, Katakami Nobuyuki, Hirata Yukio, Yatabe Yasushi

Abstract excerpt

The aim of this study was to compare the accuracy of the QuantStudio 3D Digital polymerase chain reaction (dPCR) system and a PCR-based next generation sequencing (NGS) system for detecting a secondary mutation in the epidermal growth factor receptor (EGFR) gene T790M in non-small cell lung cancer (NSCLC) patients previously diagnosed with EGFR-activating mutations. Twenty-five patients with NSCLC previously...

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Source

Identifiers

PMID: 29341374
DOI: 10.1111/pin.12630

Genes

EGFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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