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Article

Genetic Variation in the Dopamine System Influences Intervention Outcome in Children with Cerebral Palsy.

EBioMedicine - 1 Feb 2018

Diaz Heijtz Rochellys, Almeida Rita, Eliasson Ann Christin, Forssberg Hans

Abstract excerpt

BACKGROUND: There is large variation in treatment responses in children with cerebral palsy. Experimental and clinical results suggest that dopamine neurotransmission and brain-derived neurotrophic factor (BDNF) signalling are involved in motor learning and plasticity, which are key factors in modern habilitation success. We examined whether naturally occurring variations in dopamine and BDNF genes influenced the...

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Identifiers

PMID: 29339100
DOI: 10.1016/j.ebiom.2017.12.028
PMCID: PMC5835543

Genes

BDNF
COMT
DRD1
DRD2
DRD3

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