Article
Genetic variation in dopamine neurotransmission and motor development of infants born extremely-low-birthweight.
Developmental medicine and child neurology - 1 Jun 2020
Worley Gordon, Erickson Stephen W, Gustafson Kathryn E, Nikolova Yuliya S, Ashley-Koch Allison E, Belsky Daniel W, Goldstein Ricki F, Page Grier P, Cotten C Michael
Abstract excerpt
AIM: To determine if genetic variation associated with decreased dopamine neurotransmission predicts a decrease in motor development in a convenience cohort study of infants born extremely-low-birthweight (ELBW). METHOD: Four hundred and ninety-eight infants born ELBW had genome-wide genotyping and a neurodevelopmental evaluation at 18 to 22 months of age, corrected for preterm birth. A polygenic risk score (PRS)...
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