Article
Genetically Low Vitamin D Levels, Bone Mineral Density, and Bone Metabolism Markers: a Mendelian Randomisation Study.
Scientific reports - 14 Sept 2016
Li Shan-Shan, Gao Li-Hong, Zhang Xiao-Ya, He Jin-We, Fu Wen-Zhen, Liu Yu-Juan, Hu Yun-Qiu, Zhang Zhen-Lin
Abstract excerpt
Low serum 25-hydroxyvitamin D (25OHD) is associated with osteoporosis and osteoporotic fracture, but it remains uncertain whether these associations are causal. We conducted a Mendelian randomization (MR) study of 1,824 postmenopausal Chinese women to examine whether the detected associations between serum 25OHD and bone mineral density (BMD) and bone metabolism markers were causal. In observational analyses,...
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