Article
The role of the PI3K/mTOR signaling pathway in Staphylococcus epidermidis small colony variants intracellular survival.
Immunological investigations - 1 Apr 2018
Magryś Agnieszka, Bogut Agnieszka, Kiełbus Michał, Olender Alina
Abstract excerpt
The objective of this study was to analyze how Staphylococcus epidermidis SCV and WT strains manipulate the PI3K/Akt/mTOR signaling pathway. Six S. epidermidis strains with normal phenotype (WT) and six S. epidermidis strains with SCV phenotype were isolated in parallel from six patients with the prosthetic hip joint infections. THP-1 activated cells were incubated with or without PI3K inhibitor-wortmannin or...
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