Article
EGFR mutations and tumor metastases in patients with nonsmall cell lung cancer in the South of Russia.
Journal of B.U.ON. : official journal of the Balkan Union of Oncology - 1 Jan 2000
Kit Oleg I, Vodolazhsky Dmitry I, Timoshkina Natalia N, Vladimirova Lubov' Yu, Turkin Igor N, Kutsyn Ksenia A, Enin Yaroslav S, Panina Svetlana B, Jurisic Vladimir
Abstract excerpt
PURPOSE: To assess the frequencies of somatic EGFR mutations in the tumor tissues of patients with non-small cell lung cancer (NSCLC) residing in the South of Russia (SR), and to define the relationship between genetic subtypes of NSCLC and the emergence of different types of metastases. METHODS: DNA was extracted from formalin-fixed parrafin embedded (FFPE) samples of 721 patients. A total of 29 somatic EGFR...
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