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Probabilistic data integration identifies reliable gametocyte-specific proteins and transcripts in malaria parasites

5 Jan 2018

Abstract excerpt

Plasmodium gametocytes are the sexual forms of the malaria parasite essential for transmission to mosquitoes. To better understand how gametocytes differ from asexual blood-stage parasites, we performed a systematic analysis of available 'omics data for P. falciparum and other Plasmodium species. 18 transcriptomic and proteomic data sets were evaluated for the presence of curated "gold standards" of 41...

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PMID: 29323249
DOI: 10.1038/s41598-017-18840-7

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