Integrated transcriptomic and proteomic analyses of <i>P. falciparum</i> gametocytes: molecular insight into sex-specific processes and translational repression

Abstract excerpt

Sexual differentiation of malaria parasites into gametocytes in the vertebrate host and subsequent gamete fertilization in mosquitoes is essential for the spreading of the disease. The molecular processes orchestrating these transitions are far from fully understood. Here, we report the first transcriptome analysis of male and female Plasmodium falciparum gametocytes coupled with a comprehensive proteome...

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