Article
Multi-clonal evolution of multi-drug-resistant/extensively drug-resistant Mycobacterium tuberculosis in a high-prevalence setting of Papua New Guinea for over three decades.
Microbial genomics - 1 Feb 2018
Bainomugisa Arnold, Lavu Evelyn, Hiashiri Stenard, Majumdar Suman, Honjepari Alice, Moke Rendi, Dakulala Paison, Hill-Cawthorne Grant A, Pandey Sushil, Marais Ben J, Coulter Chris, Coin Lachlan
Abstract excerpt
An outbreak of multi-drug resistant (MDR) tuberculosis (TB) has been reported on Daru Island, Papua New Guinea. Mycobacterium tuberculosis strains driving this outbreak and the temporal accrual of drug resistance mutations have not been described. Whole genome sequencing of 100 of 165 clinical isolates referred from Daru General Hospital to the Supranational reference laboratory, Brisbane, during 2012-2015...
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