Article
Cancer genetics and reproduction.
Best practice & research. Clinical obstetrics & gynaecology - 1 Feb 2010
Hanson Helen, Hodgson Shirley
Abstract excerpt
Cancers of the reproductive organs (i.e., ovaries, uterus and testes), like other cancers, occur as a result of a multi-stage interaction of genetic and environmental factors. A small proportion of cancers of the reproductive organs occur as part of a recognised cancer syndrome, as a result of inheritance of mutations in highly penetrant cancer susceptibility genes (e.g., BRCA1, BRCA2, MLH1 or MSH2). Recognition...
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