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Article

Higher schizotypy predicts better metabolic profile in unaffected siblings of patients with schizophrenia.

Psychopharmacology - 1 Apr 2018

Atbasoglu E Cem, Gumus-Akay Guvem, Guloksuz Sinan, Saka Meram Can, Ucok Alp, Alptekin Koksal, Gullu Sevim, van Os Jim

Abstract excerpt

RATIONALE: Type 2 diabetes (T2D) is more frequent in schizophrenia (Sz) than in the general population. This association is partly accounted for by shared susceptibility genetic variants. OBJECTIVE: We tested the hypotheses that a genetic predisposition to Sz would be associated with higher likelihood of insulin resistance (IR), and that IR would be predicted by subthreshold psychosis phenotypes. METHODS:...

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PMID: 29306964
DOI: 10.1007/s00213-017-4818-z

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