Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variants in ADAMTS13 as well as smoking are major determinants of plasma ADAMTS13 levels

19 Jun 2017

Abstract excerpt

variants in the top 2 independent linkage disequilibrium blocks (Q448E and A732V) were identified and characterized in vitro. This study uncovered specific common genetic polymorphisms that are key genetic determinants of the variation in plasma ADAMTS13 levels in healthy individuals.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Complement system in diseases
Share to Neuropeptides and Animal Physiology
Share to Peptidase Inhibition and Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29296746
DOI: 10.1182/bloodadvances.2017005629

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variants in ADAMTS13 as well as smoking are major determinants of plasma ADAMTS13 levelsPMID 29296746Read ↗

SNPs in ADAMTS13.Semantic proximity Read ↗

Genetic variants in the ADAMTS13 and SUPT3H genes are associated with ADAMTS13 activity.Semantic proximity Read ↗

Mutations and Common Polymorphisms in ADAMTS13 and vWF Genes Responsible for Increasing Risk of Thrombosis.Semantic proximity Read ↗

Genetic Variation in ADAMTS13 is Related to VWF Levels, Atrial Fibrillation and Cerebral Ischemic Events.Semantic proximity Read ↗

Rare Variants in the ADAMTS13 Von Willebrand Factor-Binding Domain Contribute to Pediatric Stroke.Semantic proximity Read ↗

Next-Generation Sequencing and In Vitro Expression Study of ADAMTS13 Single Nucleotide Variants in Deep Vein Thrombosis.Semantic proximity Read ↗

Genomic Landscape and Mutational Spectrum of ADAMTS Family Genes in Mendelian Disorders Based on Gene Evidence Review for Variant Interpretation.Semantic proximity Read ↗

Missense Variants of von Willebrand Factor in the Background of COVID-19 Associated Coagulopathy.Semantic proximity Read ↗

Single-nucleotide variations defining previously unreported ADAMTS13 haplotypes are associated with differential expression and activity of the VWF-cleaving protease in a Salvadoran congenital thrombotic thrombocytopenic purpura family.Semantic proximity Read ↗

The global carrier frequency and genetic prevalence of Upshaw-Schulman syndromeSemantic proximity Read ↗

GWA study for ADAMTS13 activity.Semantic proximity Read ↗

The global carrier frequency and genetic prevalence of Upshaw-Schulman syndromeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.