Range Expansion and the Origin of USA300 North American Epidemic Methicillin-Resistant Staphylococcus aureus.

doi:10.1128/mBio.02016-17

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Article

Range Expansion and the Origin of USA300 North American Epidemic Methicillin-Resistant Staphylococcus aureus.

mBio - 2 Jan 2018

Challagundla Lavanya, Luo Xiao, Tickler Isabella A, Didelot Xavier, Coleman David C, Shore Anna C, Coombs Geoffrey W, Sordelli Daniel O, Brown Eric L, Skov Robert, Larsen Anders Rhod, Reyes Jinnethe, Robledo Iraida E, Vazquez Guillermo J, Rivera Raul, Fey Paul D, Stevenson Kurt, Wang Shu-Hua, Kreiswirth Barry N, Mediavilla Jose R, Arias Cesar A, Planet Paul J, Nolan Rathel L, Tenover Fred C, Goering Richard V, Robinson D Ashley

Abstract excerpt

The USA300 North American epidemic (USA300-NAE) clone of methicillin-resistant Staphylococcus aureus has caused a wave of severe skin and soft tissue infections in the United States since it emerged in the early 2000s, but its geographic origin is obscure. Here we use the population genomic signatures expected from the serial founder effects of a geographic range expansion to infer the origin of USA300-NAE and...

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PMID: 29295910
DOI: 10.1128/mBio.02016-17
PMCID: PMC5750399

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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