Article
Epidemic community-associated methicillin-resistant Staphylococcus aureus: recent clonal expansion and diversification.
Proceedings of the National Academy of Sciences of the United States of America - 29 Jan 2008
Kennedy Adam D, Otto Michael, Braughton Kevin R, Whitney Adeline R, Chen Liang, Mathema Barun, Mediavilla Jose R, Byrne Kelly A, Parkins Larye D, Tenover Fred C, Kreiswirth Barry N, Musser James M, DeLeo Frank R
Abstract excerpt
Emerging and re-emerging infectious diseases, especially those caused by drug-resistant bacteria, are a major problem worldwide. Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) appeared rapidly and unexpectedly in the United States, resulting in an epidemic caused primarily by isolates classified as USA300. The evolutionary and molecular underpinnings of this epidemic are poorly...
Topics
- Animals
- Community-Acquired Infections
- Disease Models, Animal
- Disease Outbreaks
- Drug Resistance, Multiple, Bacterial
- Genetic Variation
- Genome, Bacterial
- Humans
- Methicillin Resistance