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Article

Genetic variation in spatio-temporal confined USA300 community-associated MRSA isolates: a shift from clonal dispersion to genetic evolution?

PloS one - 4 Feb 2011

Carpaij Neeltje, Willems Rob J L, Rice Thomas W, Weinstein Robert A, Hinds Jason, Witney Adam A, Lindsay Jodi A, Bonten Marc J M, Fluit Ad C

Abstract excerpt

INTRODUCTION: Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) are increasingly isolated, with USA300-0114 being the predominant clone in the USA. Comparative whole genome sequencing of USA300 isolates collected in 2002, 2003 and 2005 showed a limited number of single nucleotide polymorphisms and regions of difference. This suggests that USA300 has undergone rapid clonal expansion...

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Identifiers

PMID: 21326601
DOI: 10.1371/journal.pone.0016419
PMCID: PMC3033884

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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