Article
Toward an understanding of the evolution of Staphylococcus aureus strain USA300 during colonization in community households.
Genome biology and evolution - 1 Jan 2012
Uhlemann Anne-Catrin, Kennedy Adam D, Martens Craig, Porcella Stephen F, Deleo Frank R, Lowy Franklin D
Abstract excerpt
Staphylococcus aureus is a frequent cause of serious infections and also a human commensal. The emergence of community-associated methicillin-resistant S. aureus led to a dramatic increase in skin and soft tissue infections worldwide. This epidemic has been driven by a limited number of clones, such as USA300 in the United States. To better understand the extent of USA300 evolution and diversification within...
Topics
- Adaptation, Biological
- Community-Acquired Infections
- Evolution, Molecular
- Genes, Bacterial
- Genome, Bacterial
- Humans
- INDEL Mutation
- Phylogeny
- Point Mutation
- Polymorphism, Single Nucleotide