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Article

The ABC Transporter Eato Promotes Cell Clearance in the Drosophila melanogaster Ovary.

G3 (Bethesda, Md.) - 2 Mar 2018

Santoso Clarissa S, Meehan Tracy L, Peterson Jeanne S, Cedano Tiara M, Turlo Christopher V, McCall Kimberly

Abstract excerpt

The clearance of dead cells is a fundamental process in the maintenance of tissue homeostasis. Genetic studies in Drosophila melanogaster, Caenorhabditis elegans, and mammals have identified two evolutionarily conserved signaling pathways that act redundantly to regulate this engulfment process: the ced-1/-6/-7 and ced-2/-5/-12 pathways. Of these engulfment genes, only the ced-7/ABCA1 ortholog remains to be...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29295819
DOI: 10.1534/g3.117.300427
PMCID: PMC5844305

Genes

ABCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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