Article
Integrative analysis reveals disrupted pathways regulated by microRNAs in cancer.
Nucleic acids research - 16 Feb 2018
Wilk Gary, Braun Rosemary
Abstract excerpt
MicroRNAs (miRNAs) are small endogenous regulatory molecules that modulate gene expression post-transcriptionally. Although differential expression of miRNAs have been implicated in many diseases (including cancers), the underlying mechanisms of action remain unclear. Because each miRNA can target multiple genes, miRNAs may potentially have functional implications for the overall behavior of entire pathways....
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