Article
Colon dysregulation in methamphetamine self-administering HIV-1 transgenic rats.
PloS one - 1 Jan 2018
Persons Amanda L, Bradaric Brinda D, Dodiya Hemraj B, Ohene-Nyako Michael, Forsyth Christopher B, Keshavarzian Ali, Shaikh Maliha, Napier T Celeste
Abstract excerpt
The integrity and function of the gut is impaired in HIV-infected individuals, and gut pathogenesis may play a role in several HIV-associated disorders. Methamphetamine is a popular illicit drug abused by HIV-infected individuals. However, the effect of methamphetamine on the gut and its potential to exacerbate HIV-associated gut pathology is not known. To shed light on this scenario, we evaluated colon barrier...
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