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Article

Molecular basis of complement factor I deficiency in Tunisian atypical haemolytic and uraemic syndrome patients.

Nephrology (Carlton, Vic.) - 1 Mar 2019

Jlajla Hend, Dehman Fatma, Jallouli Manel, Khedher Rania, Ayadi Imen, Zerzeri Yosr, Laadhar Lilia, Sfar Imen, Mahfoudh Abdelmajid, Gorgi Yosr, Cheour Elhem, Zouaghi Karim, Gargah Tahar, Kallel Sellami Maryam

Abstract excerpt

AIM: The aim of the present study was to characterize the molecular basis of complement factor I deficiency in Tunisian atypical haemolytic and uremic syndrome patients with low factor I levels. METHODS: Six adults and seven children were enrolled in this study. Complement factor I levels were assessed by a homemade sandwich ELISA and ranged between 12.5% and 60%. Genomic DNA was amplified by way of a polymerase...

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PMID: 29292855
DOI: 10.1111/nep.13217

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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