Article
Evaluation of ADAMTS17 in Chinese Shar-Pei with primary open-angle glaucoma, primary lens luxation, or both.
American journal of veterinary research - 1 Jan 2018
Oliver James A C, Rustidge Sophie, Pettitt Louise, Jenkins Christopher A, Farias Fabiana H G, Giuliano Elizabeth A, Mellersh Cathryn S
Abstract excerpt
OBJECTIVE To evaluate the coding regions of ADAMTS17 for potential mutations in Chinese Shar-Pei with a diagnosis of primary open-angle glaucoma (POAG), primary lens luxation (PLL), or both. ANIMALS 63 Shar-Pei and 96 dogs of other breeds. PROCEDURES ADAMTS17 exon resequencing was performed on buccal mucosal DNA from 10 Shar-Pei with a diagnosis of POAG, PLL, or both (affected dogs). A candidate causal variant...
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