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Article

Impact of alcohol dehydrogenase-aldehyde dehydrogenase polymorphism on clinical outcome in patients with hypopharyngeal cancer.

Head & neck - 1 Apr 2018

Avinçsal Mehmet Ozgur, Shinomiya Hirotaka, Teshima Masanori, Kubo Mie, Otsuki Naoki, Kyota Naomi, Sasaki Ryohei, Zen Yoh, Nibu Ken-Ichi

Abstract excerpt

BACKGROUND: The purpose of this research was to investigate the association between alcohol dehydrogenase 1B (ADH1B) and aldehyde dehydrogenase 2 (ALDH2) polymorphisms and hypopharyngeal squamous cell carcinoma (SCC) survival. METHODS: We genotyped ADH1B (rs1229984) and ALDH2 (rs671) single nucleotide polymorphisms (SNPs) in 85 Japanese male patients with hypopharyngeal SCC. The independent prognostic values of...

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Identifiers

PMID: 29286190
DOI: 10.1002/hed.25050

Genes

ALDH2

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