Article
HIV-1 superinfection can occur in the presence of broadly neutralizing antibodies.
Vaccine - 25 Jan 2018
Serwanga Jennifer, Ssemwanga Deogratius, Muganga Michael, Nakiboneka Ritah, Nakubulwa Susan, Kiwuwa-Muyingo Sylvia, Morris Lynn, Redd Andrew D, Quinn Thomas C, Kaleebu Pontiano
Abstract excerpt
BACKGROUND: Superinfection of individuals already infected with HIV-1 suggests that pre-existing immune responses may not adequately protect against re-infection. We assessed high-risk female sex workers initially infected with HIV-1 clades A, D or A/D recombinants, to determine if HIV-1 broadly neutralizing antibodies were lacking prior to superinfection. METHODS: Six superinfected female sex workers previously...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.