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Article

Distinct mechanisms of regulation of the ITGA6 and ITGB4 genes by RUNX1 in myeloid cells.

Journal of cellular physiology - 1 Apr 2018

Phillips Jessica L, Taberlay Phillippa C, Woodworth Alexandra M, Hardy Kristine, Brettingham-Moore Kate H, Dickinson Joanne L, Holloway Adele F

Abstract excerpt

Integrins are transmembrane adhesion receptors that play an important role in hematopoiesis by facilitating interactions between hematopoietic cells and extracellular matrix components of the bone marrow and hematopoietic tissues. These interactions are important in regulating the function, proliferation, and differentiation of hematopoietic cells, as well as their homing and mobilization in the bone marrow. Not...

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Share to Core Binding Factor Alpha 2 Subunit
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Developmental

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Source

Identifiers

PMID: 28926098
DOI: 10.1002/jcp.26197

Genes

RUNX1
ITGB4
ITGA6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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